The SafeX ProJigsaw Killer is set to make his return to the big screen this fall.

"Saw X," the 10th installment in the successful horror movie series, sees John Kramer, aka the Jigsaw Killer, travel to Mexico for a miracle cure for cancer.

When the cure turns out to be a scam, Kramer, "armed with a newfound purpose, John returns to his work, turning the tables on the con artists" in his signature, gruesome style, according to the movie's website.

The website also says it is "the most chilling installment of the Saw franchise yet" and "explores the untold chapter of Jigsaw's most personal game."

Here's everything you need to know about the latest "Saw" film:

Must-see:The films of fall you can't miss, from 'Killers of the Flower Moon' to 'Saw X' and 'Priscilla'

When is 'Saw X' set?

While the movie is the 10th in the series, it is actually set between the first two movies.

"Saw X" was written by Peter Goldfinger and Josh Stolberg, and directed by Kevin Greutert. Mark Burg and Oren Koules serve as producers.

'Saw X' release date

The movie is set to hit theaters on Friday, Sept. 29, just in time for Halloween.

'Saw X' cast

Tobin Bell returns as John Kramer and is joined in the cast by Shawnee Smith, Synnøve Macody Lund, Steven Brand, Michael Beach and Renata Vaca, according to the movie's website.

Watch the 'Saw X' trailer

Lionsgate released a trailer for the movie on July 29.